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Abstracts AJRCMB AJRCMB Home Current Issue Articles in Press Archive AnnalsATS AnnalsATS Home Current Issue Articles in Press Archive ATS Scholar More Conference Abstracts CME Content About CME Your Exam Activity Browse Exams American Journal of Respiratory and Critical Care Medicine The most innovative science and highest quality reviews, practice guidelines, and statements in pulmonary, critical care, and sleep-related fields. American Journal of Respiratory Cell and Molecular Biology Significant and original observations in the area of pulmonary biology. Some focuses include cellular, biochemical, molecular, developmental, genetic, and immunologic studies of lung cells and molecules. Annals of the American Thoracic Society Up-to-date and authoritative coverage of adult and pediatric pulmonary and respiratory sleep medicine and adult medical critical care. ATS Scholar A peer-reviewed, online-only, open-access, education-themed journal focusing on medical education, clinical education, education research, quality improvement, and more American Journal of Respiratory and Critical Care Medicine American Journal of Respiratory Cell and Molecular Biology Annals of the American Thoracic Society ATS Scholar New Journal: ATS Scholar Introducing ATS Scholar, the American Thoracic Society Education Journal A welcome to readers of ATS Scholar from editors Nitin Seam, Trish Kritek, and Kristen Burkart. FEBRUARY 24, 2020 ATS Scholar Latest Articles Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis By combining all previous IPF genome-wide association studies, the authors have identified three novel regions of the genome identified with IPF risk and confirmed 11 of the 17 previously reported regions. These findings support recent research that shows mTOR signaling promotes lung fibrogenesis and also implicate spindle-assembly genes in the development of IPF. MARCH 1, 2020 AJRCCM PAI-1 Regulation of TGF-β1–induced Alveolar Type II Cell Senescence, SASP Secretion, and SASP-mediated Activation of Alveolar Macrophages These data suggest that PAI-1 mediates TGF-β1–induced ATII cell senescence and secretion of profibrotic mediators through inducing p16, and they also suggest that senescent ATII cells contribute to lung fibrogenesis in part by activating alveolar macrophages through secreting profibrotic and proinflammatory mediators. MARCH 2020 AJRCMB Threats to Science Advising at the Environmental Protection Agency The environmental health challenges facing our nation have never been greater. Most urgently, the broad health, economic, and social impacts of climate change are upon us and require unprecedented collaboration across the sciences to find ways to mitigate the causes, adapt to unavoidable changes, and build resilient communities. MARCH 2020 AnnalsATS Lung Microbiota Predict Clinical Outcomes in Critically Ill Patients Key features of the lung microbiome (bacterial burden and enrichment with gut-associated bacteria) predict outcomes in critically ill patients. The lung microbiome is an understudied source of clinical variation in critical illness and represents a novel therapeutic target for the prevention and treatment of acute respiratory failure. MARCH 1, 2020 AJRCCM Most Cited Most Read An Official ATS/ERS/JRS/ALAT Statement: Idiopathic Pulmonary Fibrosis: Evidence-based Guidelines for Diagnosis and Management Raghu et al. Published Online: Mar 2011 Am J Respir Crit Care Med ATS Statement Published Online: Jul 2002 Am J Respir Crit Care Med An Official ATS/IDSA Statement: Diagnosis, Treatment, and Prevention of Nontuberculous Mycobacterial Diseases Griffith et al. Published Online: Feb 2007 Am J Respir Crit Care Med Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease Vestbo et al. Published Online: Feb 2013 Am J Respir Crit Care Med An Official American Thoracic Society/European Respiratory Society Statement: Update of the International Multidisciplinary Classification of the Idiopathic Interstitial Pneumonias Travis et al. Published Online: Sep 2013 Am J Respir Crit Care Med See More Diagnosis and Treatment of Adults with Community-acquired Pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America Metlay et al. Published Online: Oct 2019 Am J Respir Crit Care Med Standardization of Spirometry 2019 Update. An Official American Thoracic Society and European Respiratory Society Technical Statement Graham et al. Published Online: Oct 2019 Am J Respir Crit Care Med Treatment of Drug-Resistant Tuberculosis. An Official ATS/CDC/ERS/IDSA Clinical Practice Guideline Nahid et al. Published Online: Nov 2019 Am J Respir Crit Care Med Novel Wuhan (2019-nCoV) Coronavirus Carlos et al. Published Online: Feb 2020 Am J Respir Crit Care Med Evaluation and Management of Obesity Hypoventilation Syndrome. An Official American Thoracic Society Clinical Practice Guideline Mokhlesi et al. Published Online: Aug 2019 Am J Respir Crit Care Med See More CME Mechanical Ventilation for Acute Respiratory Distress Syndrome during Extracorporeal Life Support. Research and Practice Abrams et al. March 1, 2020 AJRCCM Beyond the Lungs: Systemic Manifestations of Pulmonary Arterial Hypertension Nickel et al. January 15, 2020 AJRCCM Approaching Clinical Trials in Childhood Interstitial Lung Disease and Pediatric Pulmonary Fibrosis Deterding et al. November 15, 2019 AJRCCM Patient Registries in Idiopathic Pulmonary Fibrosis Culver et al. July 15, 2019 AJRCCM See More In the News Sugary Diet During Pregnancy May Increase Asthma Risk in Children New York Times December 8, 2017 AnnalsATS Counting The Heavy Cost Of Care In The Age Of Opioids NPR Health October 27, 2017 AnnalsATS Vaping may cause unique health problems as dangerous as smoking cigarettes, finds study The Independent October 24, 2017 AJRCCM U.S. Opioid Deaths Nearly Doubled Since 2009 Time August 29, 2017 AnnalsATS Heart, Lung Problems May Not Always Need ICU Care Philadelphia Inquirer February 17, 2017 AnnalsATS See More Podcasts Out of the Blue Drs. Nitin Seam, Trish Kritek, and John Fleetham AJRCCM Clinician to Clinician Dr. Gregory Tino AnnalsATS The Lung Science Podcast Variety of Hosts AJRCMB Social AJRCCM Twitter AJRCMB Twitter AnnalsATS Twitter ATS Scholar Twitter 25 Broadway New York, NY 10004 United States of America (212) 315-8600 ATS Journals AJRCCM Home AJRCMB Home AnnalsATS Home ATS Documents Podcasts Services Advertising and Recruitment Press Releases Permissions Reprints and E-Prints Subscriptions General Information About the ATS Journals ATS Copyright Notice Contact Us For Agents RSS Feeds Author Use Policies ATS Homepage Terms of Use Privacy Policy Copyright © 1987-2019 American Thoracic Society, All Rights Reserved. The content on this site is intended for health professionals. Advertisements on this site do not constitute a guarantee or endorsement by the journal, society, or publisher of the quality or value of such product or of the claims made for it by its manufacturer....